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Medimabs/Substance P Rat Monoclonal Antibody (NC1/34)/MM-0001-1 -- anti-Substance P/0.5 mL
来自 : 发布时间:2024-12-25
  • Product NameSubstance P Rat Monoclonal Antibody (NC1/34)
  • HostRat
  • ClonalityMonoclonal
  • Research Area(s)Neuroscience, Cancer, Metabolism
  • ImmunogenSubstance P
  • Clone IDNC1/34
  • DataSHEET View Datasheet (PDF)
  • IsotypeIgG2a
  • ConjugationNone
  • ReactivityThis antibody recognizes the COOH-terminal end of substance P. It does not recognize Leu- or Met enkephalin, somatostatin or beta-endorphin; cross-reactivity with eledoisin: 5%. It recognizes Substance P in postmortem tissue of the human brain.
  • Specificitypredicted to all mammalian species, crab and pigeon
  • Storage BufferTissue culture supernatant
  • Format0.5 mL
  • BackgroundThe discovery of substance P (SP) was reported in 1931. After more than 70 years of investigation, SP is perhaps the best understood neuropeptide transmitter. Substance P is an undecapeptide, which by the mid-1980s was recognized to belong to the tachykinin peptide family; it is also member of the neurokinins. It has been proposed that SP, released from primary afferent nerve endings, plays a role in chronic inflammation and pain. Neurotransmitters appear to play a key role in the regulation of emotions and antagonists of their receptors may be novel psychotropic drugs of the future.

本文链接: http://medimabs.immuno-online.com/view-1468247309.html

发布于 : 2024-12-25 阅读()