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Medimabs/Substance P Rat Monoclonal Antibody (NC1/34)/MM-0001-1 -- anti-Substance P/0.5 mL
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发布时间：2024-05-19
- Product NameSubstance P Rat Monoclonal Antibody (NC1/34)
- HostRat
- ClonalityMonoclonal
- Research Area(s)Neuroscience, Cancer, Metabolism
- ImmunogenSubstance P
- Clone IDNC1/34
- DataSHEET View Datasheet (PDF)
- IsotypeIgG2a
- ConjugationNone
- ReactivityThis antibody recognizes the COOH-terminal end of substance P. It does not recognize Leu- or Met enkephalin, somatostatin or beta-endorphin; cross-reactivity with eledoisin: 5%. It recognizes Substance P in postmortem tissue of the human brain.
- Specificitypredicted to all mammalian species, crab and pigeon
- Storage BufferTissue culture supernatant
- Format0.5 mL
- BackgroundThe discovery of substance P (SP) was reported in 1931. After more than 70 years of investigation, SP is perhaps the best understood neuropeptide transmitter. Substance P is an undecapeptide, which by the mid-1980s was recognized to belong to the tachykinin peptide family; it is also member of the neurokinins. It has been proposed that SP, released from primary afferent nerve endings, plays a role in chronic inflammation and pain. Neurotransmitters appear to play a key role in the regulation of emotions and antagonists of their receptors may be novel psychotropic drugs of the future.
本文链接： http://medimabs.immuno-online.com/view-1468247309.html
发布于 ： 2024-05-19
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