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Medimabs/Growth Hormone-Releasing Hormone Sheep Polyclonal Antibody/50 µL/MM-0285
Medimabs/Growth Hormone-Releasing Hormone Sheep Polyclonal Antibody/50 µL/MM-0285
商品编号：
MM-0285
品牌：
Medimabs inc
市场价：
¥4100.00
美元价：
3280.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Target:
Growth Hormone-Releasing Hormone
Target background:
GHRH belongs to the glucagon family produced in the hypothalamus. It is essential for normal linear growth and has important metabolic effects throughout life. GHRH stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary. GHRH is released from neurosecretory nerve terminals of arcuate neurons, and is carried by the hypothalamo-hypophyseal portal system to the anterior pituitary gland, where it stimulates growth hormone(GH) secretion by stimulating the growth hormone-releasing hormone receptor.
Target alias:
GHRH, Somatocrinin, Somatoliberin, GH-RH, Growth hormone–releasing factor (GHRF or GRF), Somatotropin-releasing hormone (SRH), Somatotropin-releasing factor (SRF), Somatorelin
Immunogen:
synthetic rat GHRH (1-29)NH2
Specificity: The antibody recognizes the rat GHRH and it shows no cross-reactivity with SRIF-14, SRIF-28 rGH, LH, FSH, PRL calcitonin, insulin, glucagon ovine CRF, secretin, vasoactive intestinal peptide, and cholecystokinin-8
Clone ID:
---
Preservative:
None
Format:
Lyophilized serum
Recommend starting dilution:
If reconstituted with deionized water in 50 µl: IHC: 1:15000; In vivo Passive Immunization: neat serum; RIA: In a RIA for rGRF-(1043), at a final dilution of 1: 785,000, this antiserum binds 35% of [125I]-rGRF and can detect 7pg/assay tube. Optimal dilution has to be determined by the user.
Limitations:
Research Use Only
References:
1.-Stroh T - Subcellular dynamics of somatostatin receptor subtype 1 in the rat arcuate nucleus: receptor localization and synaptic connectivity vary in paralle...
2.-Tannenbaum GS - Interrelationship between the novel peptide ghrelin and somatostatin/growth hormone-releasing hormone in regulation of pulsatile growth hormone sec...
3.-Tannenbaum GS - Cysteamine-induced enhancement of growth hormone-releasing factor (GRF) immunoreactivity in arcuate neurons: morphological evidence for putative so...
4.-Tannenbaum GS - Mechanisms of impaired growth hormone secretion in genetically obese Zucker rats: roles of growth hormone-releasing factor and somatostatin.
Storage:
Lyophilized antibodies can be kept at 4ºC for up to 3 months and should be kept at -20ºC for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80ºC) or kept at 4ºC for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy.
品牌介绍
Medimabs让我们的专家团队为您定制抗体的开发确定最佳方法：肽，蛋白质或DNA免疫。受益于他们的专业战略建议，可靠的抗原设计和快速合成抗体开发中最关键的一步是抗原策略和设计。为了使您的项目成功的机会最大化，我们将深入分析目标的结构，并找到最佳的选择以获得适合您的应用需求的抗体。整个项目可以根据您的最终应用进行定制（流式细胞仪，治疗，蛋白质印迹，免疫荧光，ELISA，免疫沉淀等）。我们可以获得广泛的免疫原，并且每种免疫原都有其优势。 合成肽蛋白质（细菌，酵母，昆虫或哺乳动物细胞表达模型） DNA免疫让我们指导您，为您的项目设计最佳抗原。
