Medimabs/HHV-6变体A IE2小鼠单克隆抗体（P6H8）/100µg/MM-0071-P
商品编号：
MM-0071-P
品牌：
Medimabs inc
市场价：
¥6900.00
美元价：
5520.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Target:
HHV-6 Variant A IE2
Target background:
HHV-6 is a double stranded DNA virus belonging to the betaherpesvirinae subfamily. HHV-6 viruses comprise two distinct species: HHV-6A and HHV-6B. HHV-6 is a T-cell lymphotropic virus with high affinity for CD4 lymphocytes and is capable of infecting virtually all human beings.HHV-6B is responsible for at least 97% of HHV-6 infections in the USA while HHV-6A is frequently associated with patients with neuroinflammatory diseases such as multiple sclerosis. HHV-6A and HHV-6B proteins share more than 92% of their amino acids composition. However, the immediate-early protein locus A, has less than 70% of homology between the two species. At this locus, IE1 and IE2 proteins are encoded with IE2 being the most divergent between HHV-6A and HHV-6B. IE2 is expressed within few hours’ post-infection and is a potent transactivator of multiple cellular and viral promoters.
Target alias:
Immediate-early protein 2, U90/U87/U86, BCLF0
Immunogen:
Full length IE2
Specificity: The antibody recognizes the extracellular domain (aa 1078-1089 ) of protein IE2
Clone ID:
P6H8
Isotype:
IgG1 kappa
Preservative:
None
Format:
Lyophilized protein G purified in PBS pH7.4
Recommend starting dilution:
If reconstituted with deionized water in 100 µL: IF 1:50 to 1:500. Optimal dilution has to be determined by the user.
Limitations:
Research Use Only
References:
1.-Arsenault S - Generation and characterization of a monoclonal antibody specific for human herpesvirus 6 variant A immediate-early 2 protein.
2.-Tomoiu A and Flamand L - Epitope mapping of a monoclonal antibody specific for human herpesvirus 6 variant A immediate-early 2 protein.
Storage:
Lyophilized antibodies can be kept at 4ºC for up to 3 months and should be kept at -20ºC for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80ºC) or kept at 4ºC for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy.
品牌介绍
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