Medimabs/Huntingtin相互作用蛋白1（HIP1）兔多克隆抗体/100µL/MM-0031
商品编号：
MM-0031
品牌：
Medimabs inc
市场价：
¥7100.00
美元价：
5680.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Target:
Huntingtin-Interacting Protein 1 (HIP1)
Target background:
Hungtinton’s disease (HD) is an inherited neurodegenerative disorder characterized by the expression of an expanded polyglutamine tract in the protein huntingtin.HIP1 (huntingtin interacting protein 1) binds to normal huntingtin but this interaction is lost in HD.HIP1 also binds to components of clathrin-coated pits and vesicles and is a marker of clathrin-coated membranes.HIP1 expression levels are altered in several types of cancer.
Target alias:
HIP1
Immunogen:
peptide in C term
Specificity: The antibody recognizes the C-terminal portion of HIP1
Clone ID:
---
Preservative:
None
Format:
Immunogen affinity purified in glycerol/PBS pH7.4
Recommend starting dilution:
If diluted with deionized water in 100 µL: WB 1:500-1:2500; IF 1:10-1:100.Optimal dilution has to be determined by the user.
Limitations:
Research Use Only
References:
1.-Engqvist-Goldstein AE - An actin-binding protein of the Sla2/Huntingtin interacting protein 1 family is a novel component of clathrin-coated pits and vesicles.
2.-Kalchman MA - HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain.
3.-Rao DS - Huntingtin-interacting protein 1 is overexpressed in prostate and colon cancer and is critical for cellular survival.
Storage:
Antibodies diluted in glycerol can be kept at 4ºC for up to 2 months and should be kept at -20ºC for long-term storage (1 year). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. After the maximum long-term storage period (1 year -20ºC or 2 months 4ºC) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy.
品牌介绍
Medimabs让我们的专家团队为您定制抗体的开发确定最佳方法：肽，蛋白质或DNA免疫。受益于他们的专业战略建议，可靠的抗原设计和快速合成抗体开发中最关键的一步是抗原策略和设计。为了使您的项目成功的机会最大化，我们将深入分析目标的结构，并找到最佳的选择以获得适合您的应用需求的抗体。整个项目可以根据您的最终应用进行定制（流式细胞仪，治疗，蛋白质印迹，免疫荧光，ELISA，免疫沉淀等）。我们可以获得广泛的免疫原，并且每种免疫原都有其优势。 合成肽蛋白质（细菌，酵母，昆虫或哺乳动物细胞表达模型） DNA免疫让我们指导您，为您的项目设计最佳抗原。
