Medimabs/利什曼原虫A2小鼠单克隆抗体（C9）/100µg/MM-0017-P
商品编号：
MM-0017-P
品牌：
Medimabs inc
市场价：
¥7100.00
美元价：
5680.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Target:
Leishmania A2
Target background:
Leishmania donovani is a protozoa parasite responsible for human visceral leishmaniasis. During their life cycle the parasites exist in 2 forms: as flagellated promastigote within the sandfly vector and as non-flagellated amastigote in the macrophage phagolysosomal compartment of the mammalian host. A2 protein is an amastigote-specific virulence factor that is required for Leishmania donovani parasite survival in a mammalian host.
Immunogen:
The anti-A2 antibody recognizes only the amastigote form of the A2 protein.The anti-A2 antibody recognizes the sequence QSVGPLSVGP from the parasite, Leishmania donovani.
Specificity: A sensitive antibody to Leishmania amastigote-specific A2 protein. This sequence can also be used as tag if cloned with the protein of interest. This sequence is particular to the parasite and therefore the antibody has no cross-reactivity with mammalian proteins.
Clone ID:
C9
Isotype:
IgG1
Preservative:
None
Format:
Lyophilized protein G purified in PBS pH7.4
Recommend starting dilution:
If reconstituted with deionized water in 100 µL: WB 1:100. Optimal dilution has to be determined by the user.
Limitations:
Research Use Only
References:
1.-Jaiswal AK - Immunological consequences of stress-related proteins--cytosolic tryparedoxin peroxidase and chaperonin TCP20--identified in splenic amastigotes of...
2.-Kumari S - Leishmania donovani: immunostimulatory cellular responses of membrane and soluble protein fractions of splenic amastigotes in cured patient and ham...
3.-McCall LI and Matlashewski G - Localization and induction of the A2 virulence factor in Leishmania: evidence that A2 is a stress response protein.
4.-Nascimento M - Identification and characterization of a protein-tyrosine phosphatase in Leishmania: Involvement in virulence.
5.-Zhang WW - Comparison of the A2 gene locus in Leishmania donovani and Leishmania major and its control over cutaneous infection.
6.-Carvalho FA - Diagnosis of American visceral leishmaniasis in humans and dogs using the recombinant Leishmania donovani A2 antigen.
7.-Zhang WW and Matlashewski G - Loss of virulence in Leishmania donovani deficient in an amastigote-specific protein, A2.
Storage:
Lyophilized antibodies can be kept at 4ºC for up to 3 months and should be kept at -20ºC for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80ºC) or kept at 4ºC for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy.
品牌介绍
Medimabs让我们的专家团队为您定制抗体的开发确定最佳方法：肽，蛋白质或DNA免疫。受益于他们的专业战略建议，可靠的抗原设计和快速合成抗体开发中最关键的一步是抗原策略和设计。为了使您的项目成功的机会最大化，我们将深入分析目标的结构，并找到最佳的选择以获得适合您的应用需求的抗体。整个项目可以根据您的最终应用进行定制（流式细胞仪，治疗，蛋白质印迹，免疫荧光，ELISA，免疫沉淀等）。我们可以获得广泛的免疫原，并且每种免疫原都有其优势。 合成肽蛋白质（细菌，酵母，昆虫或哺乳动物细胞表达模型） DNA免疫让我们指导您，为您的项目设计最佳抗原。
