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Medimabs/Vglut1 Mouse Monoclonal Antibody (McKA1)/100 µg/MM-0016-P
Medimabs/Vglut1 Mouse Monoclonal Antibody (McKA1)/100 µg/MM-0016-P
商品编号：
MM-0016-P
品牌：
Medimabs inc
市场价：
¥7900.00
美元价：
6320.00
产品分类：
多克隆抗体
公司分类：
Polyclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Target:
Vglut1
Target background:
Glutamate is the major excitatory neurotransmitter in the central nervous system of mammals.Vesicular glutamate transporters (VGluts) are responsible for glutamate transport from the brain into native synaptic vesicles.The level of expression of the three known transporters in the adult brain determines the amount of glutamate that is loaded into vesicles and released.
Target alias:
Vesicular glutamate transporter 1, VGluT1, Brain-specific Na(+)-dependent inorganic phosphate cotransporter, Solute carrier family 17 member 7
Immunogen:
Full Lenght VGlut1
Specificity: A highly specific and sensitive antibody for VGlut1.The antibody reveals the presence of the 58 kDa VGlut 1 protein on western blot of homogenized cerebral cortex cells lysates.It shows very precise reaction with VGlut1 epitope of human mid-frontal gyrus brain tissue in immunohistochemistry.
Clone ID:
McKA1
Isotype:
IgG2a
Preservative:
None
Format:
Lyophilized protein G purified in PBS pH7.4
Recommend starting dilution:
If reconstituted with deionized water in 100 µL: ICC / IHC 1:5,000. Optimal dilution has to be determined by the user
Limitations:
Research Use Only
References:
1.-Geissler M - Primary hippocampal neurons, which lack four crucial extracellular matrix molecules, display abnormalities of synaptic structure and function and s...
2.-Allard S - Correlation of cognitive performance and morphological changes in neocortical pyramidal neurons in aging.
3.-Seo S - Spatial learning-induced accumulation of agmatine and glutamate at hippocampal CA1 synaptic terminals.
4.-Leon WC - A novel transgenic rat model with a full Alzheimer"s-like amyloid pathology displays pre-plaque intracellular amyloid-beta-associated cognitive imp...
5.-Ellegood J - Anatomical phenotyping in a mouse model of fragile X syndrome with magnetic resonance imaging.
6.-Bell KF - ADAM-10 over-expression increases cortical synaptogenesis.
7.-Bell KF - The amyloid pathology progresses in a neurotransmitter-specific manner.
Storage:
Lyophilized antibodies can be kept at 4ºC for up to 3 months and should be kept at -20ºC for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80ºC) or kept at 4ºC for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy.
品牌介绍
Medimabs让我们的专家团队为您定制抗体的开发确定最佳方法：肽，蛋白质或DNA免疫。受益于他们的专业战略建议，可靠的抗原设计和快速合成抗体开发中最关键的一步是抗原策略和设计。为了使您的项目成功的机会最大化，我们将深入分析目标的结构，并找到最佳的选择以获得适合您的应用需求的抗体。整个项目可以根据您的最终应用进行定制（流式细胞仪，治疗，蛋白质印迹，免疫荧光，ELISA，免疫沉淀等）。我们可以获得广泛的免疫原，并且每种免疫原都有其优势。 合成肽蛋白质（细菌，酵母，昆虫或哺乳动物细胞表达模型） DNA免疫让我们指导您，为您的项目设计最佳抗原。
