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当前位置: 首页 > 产品中心 > monoclonal_antibody > Medimabs/Anti-RPTPsigma Mouse Monoclonal Antibody - Purified/MM-0020-P -- Purified Receptor protein tyrosine phosphatase
商品详细Medimabs/Anti-RPTPsigma Mouse Monoclonal Antibody - Purified/MM-0020-P -- Purified Receptor protein tyrosine phosphatase
Medimabs/Anti-RPTPsigma Mouse Monoclonal Antibody - Purified/MM-0020-P -- Purified Receptor protein tyrosine phosphatase
Medimabs/Anti-RPTPsigma Mouse Monoclonal Antibody - Purified/MM-0020-P -- Purified Receptor protein tyrosine phosphatase
市场价: ¥7860.00
美元价: 6288.00
产地: 美国(厂家直采)
公司:
产品分类: 单克隆抗体
公司分类: monoclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Product Name
    Anti-RPTPsigma Mouse Monoclonal Antibody - Purified
  • Host
    Mouse
  • Clonality
    Monoclonal
  • Research Area(s)
    Signal Transduction, Cell Biology, Immunology, Cancer
  • Immunogen
    recombinant protein corresponding to the intracellular domain of mouse RPTP .
  • Clone ID
    17G7.2
  • DataSHEET
    View Datasheet (PDF)
  • Isotype
    IgG1 Kappa chain
  • Conjugation
    None
  • Reactivity
    The antibody recognizes the intracellular sub-unit of RPTPσ
  • Specificity
    Mouse, Human, Monkey
  • Storage Buffer
    PBS
  • Format
    100 µg
  • Background
    Type IIa receptor protein tyrosine phosphatases (RPTPs) are a group of well-characterized proteins that are involved in axon growth and guidance during neural development. Members of this subfamily, RPTPσ, RPTPδ and LAR contain two cytoplasmic phosphatase domains and extracellular immunoglobulin domains followed by fibronectin type III repeats. RPTPσ is a type I transmembrane protein that has an apparent molecular weight of approximately 80 kDa. It is highly expressed by neurons in developing and adult mammalian nervous system. Knock-out mice for RPTPσ show growth retardation, delayed peripheral nerve development and high mortality rates. The role of RPTPσ in axon guidance during development suggests it could influence axon regeneration after injury in the adult mouse. It has been shown that RPTPσ slows axon regeneration in the adult injured CNS.
品牌介绍
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